Major depressive disorder (MDD) is common and affects overall quality of life. For patients who have not found relief through traditional antidepressants, alternative options like Spravato are available. Understanding how this treatment works and what to expect during the process can help you prepare. Here is more information on Spravato treatment and how it works:
What Is Spravato Treatment?
Spravato is the brand name for esketamine, a prescription nasal spray used to treat treatment-resistant depression in adults. It differs from standard antidepressants because it is derived from ketamine, an anesthetic used in medical settings. While traditional antidepressants target neurotransmitters like serotonin, norepinephrine, or dopamine, Spravato targets the glutamate system in the brain. Spravato treatment is designed for patients who have tried at least two other antidepressant treatments without significant improvement, and those with major depressive disorder experiencing suicidal thoughts.
What Does Spravato Treat?
Healthcare providers prescribe Spravato primarily for treatment-resistant depression (TRD) and depressive symptoms in adults with MDD with acute suicidal ideation or behavior. TRD is diagnosed when a patient struggles with depression despite trying multiple courses of adequate medication. This specific form of therapy aims to provide relief when standard pharmacological interventions have failed.
What Are the Benefits?
One of the primary benefits of Spravato is the speed at which it can reduce depressive symptoms. Unlike oral antidepressants, which may take several weeks to build up in the system and show effects, Spravato can offer noticeable relief within hours or days for some patients. This rapid onset is beneficial for individuals experiencing severe symptoms that require immediate attention.
Another benefit is its efficacy in patients who have not responded to other treatments. Adding Spravato to an oral antidepressant may result in a greater reduction of depressive symptoms compared to an oral antidepressant alone. This offers a new option for those who have felt their condition was unmanageable.
What Does the Process Involve?
The treatment process begins with a consultation to determine if Spravato is the right option for your specific medical history. Once approved, you will schedule sessions at a certified treatment center, as the medication cannot be taken at home. You will self-administer the nasal spray under the direct observation of a healthcare professional.
After administration, a mandatory observation period lasts for two hours. During this time, medical staff may monitor your blood pressure and check for side effects such as dissociation, dizziness, or sedation. You must arrange for transportation home after each session, as driving or operating heavy machinery is prohibited. Your provider will continually assess your progress to determine the appropriate duration of therapy.
How Can You Navigate Treatment?
Preparation is a key component of a successful treatment experience, and wearing comfortable clothing and bringing entertainment, such as a book or music, can help you relax during the two-hour observation window. Communicating openly with your healthcare provider about any questions is necessary for adjusting your care plan. Adhering to the schedule and continuing your prescribed oral antidepressant are valuable steps for achieving the desired outcomes.
Learn More About Treatment Today
Professional guidance will help clarify if this specific nasal spray is compatible with your medical needs. Take the time to discuss your history and options to determine the most effective path forward. Contact a local treatment center today to schedule a consultation and learn more about how Spravato can support your mental health recovery.
